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Cayman Thiocolchicine; Purity- Greater Than Or Equal To 98%; Size
List Price
$166.00
Your Price
$166.00
Cayman Thiocolchicine; Purity- Greater Than Or Equal To 98%; Size- 25 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-17427-25
MFG.PART:
17427-25
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Thiocolchicine is an inhibitor of microtubule assembly (IC50 = 2.5 µM) and a derivative of colchicine (Item No. 9000760).1 It inhibits binding of colchicine to tubulin (Ki = 0.7 µM in a radioligand binding assay). Thiocolchicine inhibits proliferation of MDA-MB-231 and multidrug resistant (MDR) MCF-7 ADRr breast cancer cells (IC50s = 0.6 and 400 nM, respectively) as well MDR CEM-VBL leukemia cells (IC50 = 50 nM).2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[(7S)-
CAS Number
2730-71-4
Synonyms
- NSC 186301
Molecular Formula
C22H25NO5S
Formula Weight
415.5
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMSO: soluble
- Ethanol: soluble
- Methanol: soluble
λmax
230, 254, 288, 379 nm
SMILES
O=C1C(SC)=CC=C2C([C@@H](NC(C)=O)CCC3=C2C(OC)=C(OC)C(OC)=C3)=C1
InChi Code
InChI=1S/C22H25NO5S/c1-12(24)23-16-8-6-13-10-18(26-2)21(27-3)22(28-4)20(13)14-7-9-19(29-5)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1
InChi Key
CMEGANPVAXDBPL-INIZCTEOSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17427-25 |
|---|---|
| Featured | No |
| Supplier Part Number | 17427-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 2730-71-4 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |
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