Cayman 2-Pyridylthioamide; Purity- Greater Than Or Equal To 98%;

List Price $11.00 Your Price $11.00
Cayman 2-Pyridylthioamide; Purity- Greater Than Or Equal To 98%; Size- 1 G; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-13043-1
MFG.PART: 13043-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description

Chetomin is a natural product isolated from Chaetomium species which has antibacterial and antifungal properties. It is a small molecule inhibitor of hypoxia-inducible factor (HIF) signaling, disrupting the binding of HIF-1α and HIF-2α to p300 at low nanomolar concentrations. Chetomin effectively attenuates the HIF pathway both in cells and in vivo, in mice. It inhibits HIF-dependant signaling, cell growth, and tumor growth in cancer cells and xenografts.,

WARNING This product is not for human or veterinary use.

Technical Information
Formal Name
2,3S,5aR,6,10bS,11-hexahydro-3-(hydroxymethyl)-10b-[(1S,4S)-3-[[4-(hydroxymethyl)-5,7-dimethyl-6,8-dioxo-2,3-dithia-5,7-diazabicyclo[2.2.2]oct-1-yl]methyl]-1H-indol-1-yl]-2-methyl-3,11aS-epidithio-11aH-pyrazino[1,2:1,5]pyrrolo[2,3-b]indole-1,4-dione
CAS Number
1403-36-7
Synonyms
  • NSC 289491
Molecular Formula
C31H30N6O6S4
Formula Weight
710.9
Purity
≥95%
Formulation
An crystalline solid
Solubility
  • DMSO: 5 mg/ml
SMILES
O=C(C1(CC2=CN([C@@]34C5=CC=CC=C5N[C@]3([H])N(C([C@@]6(CO)N(C)C7=O)=O)[C@]7(SS6)C4)C8=C2C=CC=C8)N9C)N(C)[C@@](CO)(SS1)C9=O
InChi Code
InChI=1S/C31H30N6O6S4/c1-33-25(42)30(15-38)34(2)23(40)28(33,44-46-30)12-17-13-36(21-11-7-4-8-18(17)21)27-14-29-24(41)35(3)31(16-39,47-45-29)26(43)37(29)22(27)32-20-10-6-5-9-19(20)27/h4-11,13,22,32,38-39H,12,14-16H2,1-3H3/t22-,27+,28?,29+,30+,31+/m1/s
InChi Key
ZRZWBWPDBOVIGQ-ZVZGDCBQSA-N
Origin
Fungus/Chaetomium sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
More Information
SKU CAYM-13043-1
Featured No
Supplier Part Number 13043-1
UM EA
UNSPSC 12352200
Manufacturer Name Cayman
MSDS URL Click here
Temperature -20
Refrigerated-Frozen Refrigerated
CountryOfOrigin United States
ProductLine CAYM
Qty 1
MinOrderQty 1
Weight 7.000000
Lead Time 2
Hazardous N
CAS Number 5346-38-3
Energy Star No
Green No
ACT Ecolabel No
Controlled N
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