Cayman N-Cyclohexanecarbonyltetradecylamine; Purity- Greater Than

Numerous analogs of fatty acyl ethanolamides potentiate the intrinsic biological activity of endocannabinoids.¹ This potentiation is ascribed either to inhibition of AEA reuptake into neurons, or inhibition of fatty acid amide hydrolase (FAAH) within the neurons. ² However, Ueda, et al. has recently cloned another amidase, the acidic PEAase that promotes the hydrolysis of palmitoylethanolamide.³ N-Cyclohexanecarbonyltetradecylamine is an analog of N-cyclohexanecarbonyl-pentadecylamine, a selective inhibitor of acidic PEAase with an IC₅₀ value of 4.5 µM, that contains 1 less carbon in the alkyl chain.⁴ The biological activity of N-cyclohexanecarbonyltetradecylamine has not been documented.

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