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Millipore Active, N-Terminal Gst-Tagged, Recombinant, Human Ron Amino Acids 983-End, For Use In Kinase Assays. - Mill (Additional S&H or Hazmat Fees May Apply)
N-terminal GST-tagged, recombinant, human Ron amino acids 983-end
Product Information
Quality Level
MQ100
Applications
Application
Active, N-terminal GST-tagged, recombinant, human Ron amino acids 983-end, for use in Kinase Assays.
Key Applications
Kinase Assay
Biological Information
Source
expressed by baculovirus in Sf21 insect cells
Specific Activity
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme
Entrez Gene Number
NM_002447.1
Gene Symbol
MST1R
CDw136
RON
PTK8
p185-Ron
Protein Target
Ron
Purification Method
Glutathione agarose affinity chromatography
Target Sub-Family
TK
UniProt Number
Q04912
UniProt Summary
FUNCTION: SwissProt: Q04912 # Receptor for macrophage stimulating protein (MSP). Has a tyrosine-protein kinase activity. SIZE: 1400 amino acids; 152227 Da SUBUNIT: Heterodimer formed of an alpha chain and a beta chain which are disulfide linked. Binds PLXNB1. Associates with and is negatively regulated by HYAL2. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. TISSUE SPECIFICITY: Keratinocytes and lung. PTM: Proteolytic processing yields the two subunits. & Phosphorylated in response to ligand binding (Probable). SIMILARITY: SwissProt: Q04912 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. & Contains 3 IPT/TIG domains. & Contains 1 protein kinase domain. & Contains 1 Sema domain.
Molecular Weight
74.2kDa
Product Usage Statements
Quality Assurance
routinely evaluated by phosphorylating Axltide (Catalog #12-516)
Usage Statement
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions
6 months at -70°C
Packaging Information
Material Size
10 µg
Material Package
Also available in 250 µg size --call for pricing and availability and reference catalog number 14-581M when ordering the 250 µg size.
